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Inhibition of the epigenetic regulator REST ameliorates ischemic brain injury

Cerebral ischemia is known to activate the repressor element-1 (RE1) silencing transcription factor (REST) which silences neural genes via epigenetic remodeling and promotes neurodegeneration. We presently determined if REST inhibition de-represses target genes involved in synaptic plasticity and pr...

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Foilsithe in:Mol Neurobiol
Main Authors: Morris-Blanco, Kahlilia C., Kim, TaeHee, Bertogliat, Mario J., Mehta, Suresh L., Chokkalla, Anil K., Vemuganti, Raghu
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344325/
https://ncbi.nlm.nih.gov/pubmed/30039336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1254-y
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