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Inhibition of the epigenetic regulator REST ameliorates ischemic brain injury
Cerebral ischemia is known to activate the repressor element-1 (RE1) silencing transcription factor (REST) which silences neural genes via epigenetic remodeling and promotes neurodegeneration. We presently determined if REST inhibition de-represses target genes involved in synaptic plasticity and pr...
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| Pubblicato in: | Mol Neurobiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344325/ https://ncbi.nlm.nih.gov/pubmed/30039336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1254-y |
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