Redox Activation of Nox1 Involves an Intermolecular Disulfide Bond between Protein Disulfide Isomerase and p47(phox) in Vascular Smooth Muscle Cells

OBJECTIVE: Protein disulfide isomerase A1 (PDI) was reported to support Nox1 NADPH oxidase (Nox1) activation mediated by growth factors in vascular smooth muscle cells. Our aim was to investigate the molecular mechanism by which PDI activates Nox1 and the functional implications of PDI in Nox1-activ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Gimenez, Marcela, Veríssimo-Filho, Sidney, Wittig, Ilka, Schickling, Brandon M., Hahner, Fabian, Schürmann, Christoph, Netto, Luis E.S., Rosa, José César, Brandes, Ralf P., Sartoretto, Simone, Lucca Camargo, Lívia De, Abdulkader, Fernando, Miller, Francis J., Lopes, Lucia Rossetti
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344286/
https://ncbi.nlm.nih.gov/pubmed/30580571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311038
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