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PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
The PLZF transcription factor is essential for osteogenic differentiation of hMSCs; however, its regulation and molecular function during this process is not fully understood. Here, we revealed that the ZBTB16 locus encoding PLZF, is repressed by Polycomb (PcG) and H3K27me3 in naive hMSCs. At the pr...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344081/ https://ncbi.nlm.nih.gov/pubmed/30672466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40364 |
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