Generation by phage display and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics

Anti-idiotypic antibodies play an important role in pre-clinical and clinical development of therapeutic antibodies, where they are used for pharmacokinetic studies and for the development of immunogenicity assays. By using an antibody phage display library in combination with guided in vitro select...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:MAbs
Prif Awduron: Harth, Stefan, Ten Haaf, Andre, Loew, Christian, Frisch, Christian, Knappik, Achim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2018
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343800/
https://ncbi.nlm.nih.gov/pubmed/30516449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1538723
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