Geranylgeraniol (GGOH) as a Mevalonate Pathway Activator in the Rescue of Bone Cells Treated with Zoledronic Acid: An In Vitro Study

Bisphosphonates (BPs) are the keystone to treat bone disorders. Despite the great benefits of BPs, medication-related osteonecrosis of the jaw (MRONJ) arouse as a potential side effect. Nitrogen-containing BPs (N-BPs) as zoledronate (ZA) act by the inhibition of specific enzymes of the mevalonate pa...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Fliefel, Riham M., Entekhabi, Saleh A., Ehrenfeld, Michael, Otto, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343170/
https://ncbi.nlm.nih.gov/pubmed/30728841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4351327
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