Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival

BACKGROUND: Cancer cachexia is a complex wasting syndrome affecting patients with advanced cancer, with systemic inflammation as a key component in pathogenesis. Protein degradation and release of amino acids (AAs) in skeletal muscle are stimulated in cachexia. Here, we define factors contributing t...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Sirniö, Päivi, Väyrynen, Juha P., Klintrup, Kai, Mäkelä, Jyrki, Karhu, Toni, Herzig, Karl-Heinz, Minkkinen, Ilkka, Mäkinen, Markus J., Karttunen, Tuomo J., Tuomisto, Anne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342921/
https://ncbi.nlm.nih.gov/pubmed/30563990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0357-6
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