Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

The progenitor cells of the developing liver can differentiate toward both hepatocyte and biliary cell fates. In addition to the established roles of TGFβ and Notch signaling in this fate specification process, there is increasing evidence that liver progenitors are sensitive to mechanical cues. Her...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Kaylan, Kerim B, Berg, Ian C, Biehl, Matthew J, Brougham-Cook, Aidan, Jain, Ishita, Jamil, Sameed M, Sargeant, Lauren H, Cornell, Nicholas J, Raetzman, Lori T, Underhill, Gregory H
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Developmental Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342520/
https://ncbi.nlm.nih.gov/pubmed/30589410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38536
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