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Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix

The bipotential differentiation of liver progenitor cells underlies liver development and bile duct formation as well as liver regeneration and disease. TGFβ and Notch signaling are known to play important roles in the liver progenitor specification process and tissue morphogenesis. However, the com...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kaylan, Kerim B., Ermilova, Viktoriya, Yada, Ravi Chandra, Underhill, Gregory H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812246/
https://ncbi.nlm.nih.gov/pubmed/27025873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23490
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