An RNA-based digital circulating tumor cell signature is predictive of drug response and early dissemination in prostate cancer

Blood-based biomarkers are critical in metastatic prostate cancer, where characteristic bone metastases are not readily sampled, and they may enable risk stratification in localized disease. We established a sensitive and high-throughput strategy for analyzing prostate circulating tumor cells (CTCs)...

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Udgivet i:Cancer Discov
Main Authors: Miyamoto, David T., Lee, Richard J., Kalinich, Mark, LiCausi, Joseph, Zheng, Yu, Chen, Tianqi, Milner, John D., Emmons, Erin, Ho, Uyen, Broderick, Katherine, Silva, Erin, Javaid, Sarah, Kwan, Tanya Todorova, Hong, Xin, Dahl, Douglas M., McGovern, Francis J., Efstathiou, Jason A., Smith, Matthew R., Sequist, Lecia V., Kapur, Ravi, Wu, Chin-Lee, Stott, Shannon L., Ting, David T., Giobbie-Hurder, Anita, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342192/
https://ncbi.nlm.nih.gov/pubmed/29301747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-1406
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