An RNA-based digital circulating tumor cell signature is predictive of drug response and early dissemination in prostate cancer

Blood-based biomarkers are critical in metastatic prostate cancer, where characteristic bone metastases are not readily sampled, and they may enable risk stratification in localized disease. We established a sensitive and high-throughput strategy for analyzing prostate circulating tumor cells (CTCs)...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Miyamoto, David T., Lee, Richard J., Kalinich, Mark, LiCausi, Joseph, Zheng, Yu, Chen, Tianqi, Milner, John D., Emmons, Erin, Ho, Uyen, Broderick, Katherine, Silva, Erin, Javaid, Sarah, Kwan, Tanya Todorova, Hong, Xin, Dahl, Douglas M., McGovern, Francis J., Efstathiou, Jason A., Smith, Matthew R., Sequist, Lecia V., Kapur, Ravi, Wu, Chin-Lee, Stott, Shannon L., Ting, David T., Giobbie-Hurder, Anita, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342192/
https://ncbi.nlm.nih.gov/pubmed/29301747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-1406
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