Effects of Beclin 1 overexpression on aggressive phenotypes of colon cancer cells

Beclin 1 is involved in autophagy, differentiation, apoptosis and cancer progression, and functions as a haploinsufficient tumor suppressor gene. The aim of the present study was to elucidate the function of Beclin 1 in colon cancer. A Beclin 1-expressing plasmid was transfected into HCT-15 and HCT-...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Zhang, Mei-Ying, Wang, Li-Yuan, Zhao, Shuang, Guo, Xiao-Chong, Xu, Ying-Qi, Zheng, Zhi-Hong, Lu, Hang, Zheng, Hua-Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341844/
https://ncbi.nlm.nih.gov/pubmed/30675309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9817
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