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Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays

The identification of small molecules that bind to and perturb the function of microRNAs is an attractive approach for the treatment for microRNA-associated pathologies. However, there are only a few small molecules known to interact directly with microRNAs. Here, we report the use of a small molecu...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Connelly, Colleen M., Boer, Robert E., Moon, Michelle H., Gareiss, Peter, Schneekloth, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341489/
https://ncbi.nlm.nih.gov/pubmed/27959491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00945
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