Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes

Celiac disease (CeD) provides an opportunity to study the specificity underlying human T-cell responses to an array of similar epitopes presented by the same human leukocyte antigen II (HLA-II) molecule. Here, we investigated T-cell responses to the two immunodominant and highly homologous HLA-DQ2.5...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E. A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie, Sollid, Ludvig M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341401/
https://ncbi.nlm.nih.gov/pubmed/30455354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005736
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