Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (68)Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques

BACKGROUND: Rupture-prone atherosclerotic plaques are characterized by heavy macrophage infiltration, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR, CD206) is over-expressed in several types of alternatively activated macrophages. I...

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Détails bibliographiques
Publié dans:EJNMMI Res
Auteurs principaux: Varasteh, Zohreh, Mohanta, Sarajo, Li, Yuanfang, López Armbruster, Nicolás, Braeuer, Miriam, Nekolla, Stephan G., Habenicht, Andreas, Sager, Hendrik B., Raes, Geert, Weber, Wolfgang, Hernot, Sophie, Schwaiger, Markus
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2019
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340911/
https://ncbi.nlm.nih.gov/pubmed/30666513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-019-0474-0
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