Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 111In-tilmanocept

Abstract Background Atherosclerotic plaque phenotypes are classified based on the extent of macrophage infiltration into the lesions, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR) is over-expressed in activated macrophages. Tilmano...

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Main Authors: Zohreh Varasteh, Fabien Hyafil, Nadège Anizan, Devy Diallo, Rachida Aid-Launais, Sarajo Mohanta, Yuanfang Li, Miriam Braeuer, Katja Steiger, Jonathan Vigne, Zhengtao Qin, Stephan G. Nekolla, Jean-Etienne Fabre, Yvonne Döring, Dominique Le Guludec, Andreas Habenicht, David R. Vera, Markus Schwaiger
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2017-05-01
Colecção:EJNMMI Research
Assuntos:
Non-invasive imaging
Atherosclerosis
Inflammation
M2 differentiated macrophages
SPECT/CT
Tilmanocept
Acesso em linha:http://link.springer.com/article/10.1186/s13550-017-0287-y
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