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Evidence of a Role for Functional Heterogeneity in Multidrug Resistance (MDR) Transporters in Clinical Trials of P-glycoprotein Modulation in Acute Myeloid Leukemia
BACKGROUND: Multidrug resistance (MDR) transporter proteins such as P-glycoprotein (P-gp) efflux a variety of chemotherapeutic drugs from acute myeloid leukemia (AML) blasts leading to clinical drug resistance. METHODS: This study examined heterogeneity of MDR functional efflux by AML blasts using t...
में बचाया:
| में प्रकाशित: | Cytometry B Clin Cytom |
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| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340737/ https://ncbi.nlm.nih.gov/pubmed/30334334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.21737 |
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