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Evidence of a Role for Functional Heterogeneity in Multidrug Resistance (MDR) Transporters in Clinical Trials of P-glycoprotein Modulation in Acute Myeloid Leukemia
BACKGROUND: Multidrug resistance (MDR) transporter proteins such as P-glycoprotein (P-gp) efflux a variety of chemotherapeutic drugs from acute myeloid leukemia (AML) blasts leading to clinical drug resistance. METHODS: This study examined heterogeneity of MDR functional efflux by AML blasts using t...
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| Publicado no: | Cytometry B Clin Cytom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340737/ https://ncbi.nlm.nih.gov/pubmed/30334334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.b.21737 |
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