Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome

Heat shock factor 1 is the master transcriptional regulator of molecular chaperones and binds to the same cis-acting heat shock element (HSE) across the eukaryotic lineage. In budding yeast, Hsf1 drives the transcription of ∼20 genes essential to maintain proteostasis under basal conditions, yet its...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Pincus, David, Anandhakumar, Jayamani, Thiru, Prathapan, Guertin, Michael J., Erkine, Alexander M., Gross, David S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340206/
https://ncbi.nlm.nih.gov/pubmed/30332327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0353
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