Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines

Numerous protocols have been described for producing neural retina from human pluripotent stem cells (hPSCs), many of which are based on the culture of 3D organoids. Although nearly all such methods yield at least partial segments of retinal structure with a mature appearance, variabilities exist wi...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Capowski, Elizabeth E., Samimi, Kayvan, Mayerl, Steven J., Phillips, M. Joseph, Pinilla, Isabel, Howden, Sara E., Saha, Jishnu, Jansen, Alex D., Edwards, Kimberly L., Jager, Lindsey D., Barlow, Katherine, Valiauga, Rasa, Erlichman, Zachary, Hagstrom, Anna, Sinha, Divya, Sluch, Valentin M., Chamling, Xitiz, Zack, Donald J., Skala, Melissa C., Gamm, David M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Human Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340149/
https://ncbi.nlm.nih.gov/pubmed/30567931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.171686
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