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pH-Driven RNA Strand Separation under Prebiotically Plausible Conditions

[Image: see text] Replication of nucleic acids in the absence of genetically encoded enzymes represents a critical process for the emergence of cellular life. Repeated separation of complementary RNA strands is required to achieve multiple cycles of chemical replication, yet thermal denaturation und...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Mariani, Angelica, Bonfio, Claudia, Johnson, Christopher M., Sutherland, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340128/
https://ncbi.nlm.nih.gov/pubmed/30383375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01080
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