Pharmacokinetic–pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients

AIMS: To characterize ticagrelor exposure‐response relationship for platelet inhibition in patients with stable coronary artery disease (CAD) and a history of myocardial infarction (MI), using nonlinear mixed effects modelling and simulation. METHODS: Platelet function data were integrated with plas...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Åstrand, Magnus, Amilon, Carl, Röshammar, Daniel, Himmelmann, Anders, Angiolillo, Dominick J., Storey, Robert F., Gurbel, Paul A., Bonaca, Marc P., Hamrén, Bengt
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339964/
https://ncbi.nlm.nih.gov/pubmed/30414387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13812
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi