PDL1 Fusion Protein Protects Against Experimental Cerebral Malaria via Repressing Over-Reactive CD8(+) T Cell Responses

Cerebral malaria (CM), mainly caused by Plasmodium falciparum (P. f.), is one of the most lethal complications of severe malaria. As immunopathology mediated by brain-infiltrating CD8(+) T cells is the major pathogenesis of CM, there is no safe and efficient treatment clinically focused on CD8(+) T...

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Gepubliceerd in:Front Immunol
Hoofdauteurs: Wang, Jun, Li, Yue, Shen, Yan, Liang, Jiao, Li, Yinghui, Huang, Yuxiao, Liu, Xuewu, Jiang, Dongbo, Yang, Shuya, Zhao, Ya, Yang, Kun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339951/
https://ncbi.nlm.nih.gov/pubmed/30693001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03157
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