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PDL1 Fusion Protein Protects Against Experimental Cerebral Malaria via Repressing Over-Reactive CD8(+) T Cell Responses
Cerebral malaria (CM), mainly caused by Plasmodium falciparum (P. f.), is one of the most lethal complications of severe malaria. As immunopathology mediated by brain-infiltrating CD8(+) T cells is the major pathogenesis of CM, there is no safe and efficient treatment clinically focused on CD8(+) T...
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| Publicado en: | Front Immunol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6339951/ https://ncbi.nlm.nih.gov/pubmed/30693001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03157 |
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