Sirtuin 1 and Autophagy Attenuate Cisplatin-Induced Hair Cell Death in the Mouse Cochlea and Zebrafish Lateral Line

Cisplatin-induced ototoxicity is one of the major adverse effects in cisplatin chemotherapy, and hearing protective approaches are unavailable in clinical practice. Recent work unveiled a critical role of autophagy in cell survival in various types of hearing loss. Since the excessive activation of...

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Udgivet i:Front Cell Neurosci
Main Authors: Pang, Jiaqi, Xiong, Hao, Zhan, Ting, Cheng, Gui, Jia, Haiying, Ye, Yongyi, Su, Zhongwu, Chen, Hongyu, Lin, Hanqing, Lai, Lan, Ou, Yongkang, Xu, Yaodong, Chen, Suijun, Huang, Qiuhong, Liang, Maojin, Cai, Yuexin, Zhang, Xueyuan, Xu, Xiaoding, Zheng, Yiqing, Yang, Haidi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339946/
https://ncbi.nlm.nih.gov/pubmed/30692914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00515
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