Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases

BACKGROUND: Benralizumab, a humanized, afucosylated, monoclonal antibody that targets interleukin-5 receptor α, depletes eosinophils and basophils by enhanced antibody-dependent cell-mediated cytotoxicity. It demonstrated efficacy for patients with moderate to severe asthma and, in a Phase IIa trial...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Sridhar, Sriram, Liu, Hao, Pham, Tuyet-Hang, Damera, Gautam, Newbold, Paul
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339432/
https://ncbi.nlm.nih.gov/pubmed/30658649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0968-8
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