Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens

BACKGROUND: Response surface methodology (RSM) employing Box-Behnken design was used to optimize the environmental factors for the production of paromomycin, a 2 deoxystreptamine aminocyclitol aminoglycoside antibiotic, (2DOS-ACAGA) from Streptomyces (S.) rimosus NRRL 2455. Emergence of bacterial re...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Ibrahim, Asmaa A., El-Housseiny, Ghadir S., Aboshanab, Khaled M., Yassien, Mahmoud A., Hassouna, Nadia A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339272/
https://ncbi.nlm.nih.gov/pubmed/30658584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1390-1
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