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Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Large studies use genotype data to discover genetic contributions to complex traits and infer relationships between those traits. Co-incident geographical variation in genotypes and health traits can bias these analyses. Here we show that single genetic variants and genetic scores composed of multip...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Haworth, Simon, Mitchell, Ruth, Corbin, Laura, Wade, Kaitlin H., Dudding, Tom, Budu-Aggrey, Ashley, Carslake, David, Hemani, Gibran, Paternoster, Lavinia, Smith, George Davey, Davies, Neil, Lawson, Daniel J., J. Timpson, Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338768/
https://ncbi.nlm.nih.gov/pubmed/30659178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08219-1
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