Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Large studies use genotype data to discover genetic contributions to complex traits and infer relationships between those traits. Co-incident geographical variation in genotypes and health traits can bias these analyses. Here we show that single genetic variants and genetic scores composed of multip...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Haworth, Simon, Mitchell, Ruth, Corbin, Laura, Wade, Kaitlin H., Dudding, Tom, Budu-Aggrey, Ashley, Carslake, David, Hemani, Gibran, Paternoster, Lavinia, Smith, George Davey, Davies, Neil, Lawson, Daniel J., J. Timpson, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338768/
https://ncbi.nlm.nih.gov/pubmed/30659178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08219-1
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