Tadalafil treatment in mice for preeclampsia with fetal growth restriction has neuro-benefic effects in offspring through modulating prenatal hypoxic conditions

We have demonstrated that tadalafil facilitates fetal growth in mice with L-NG-nitroarginine methyl ester (L-NAME)-induced preeclampsia (PE) with fetal growth restriction (FGR). Tadalafil is a selective phosphodiesterase 5 inhibitor that dilates the maternal blood sinuses in the placenta, thereby fa...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Tachibana, Ryota, Umekawa, Takashi, Yoshikawa, Kento, Owa, Takao, Magawa, Shoichi, Furuhashi, Fumi, Tsuji, Makoto, Maki, Shintaro, Shimada, Kyoko, Kaneda, Michiko K., Nii, Masafumi, Tanaka, Hiroaki, Tanaka, Kayo, Kamimoto, Yuki, Kondo, Eiji, Kato, Ineko, Ikemura, Kenji, Okuda, Masahiro, Ma, Ning, Miyoshi, Takekazu, Hosoda, Hiroshi, Endoh, Masayuki, Kimura, Tadashi, Ikeda, Tomoaki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338749/
https://ncbi.nlm.nih.gov/pubmed/30659198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36084-x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars