Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

Influenza B viruses (IBV) drive a significant proportion of influenza-related hospitalisations yet are understudied compared to influenza A. Current vaccines target the head of the viral hemagglutinin (HA) which undergoes rapid mutation, significantly reducing vaccine effectiveness. Improved vaccine...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Yi, Tan, Hyon-Xhi, Koutsakos, Marios, Jegaskanda, Sinthujan, Esterbauer, Robyn, Tilmanis, Danielle, Aban, Malet, Kedzierska, Katherine, Hurt, Aeron C., Kent, Stephen J., Wheatley, Adam K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338745/
https://ncbi.nlm.nih.gov/pubmed/30659197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08165-y
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