Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress

NF-E2–related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidative and electrophilic stress responses. Previous studies have shown that a regulatory connection exists between NRF2 and autophagy during reactive oxygen...

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Vydáno v:FASEB J
Hlavní autoři: Kosztelnik, Monika, Kurucz, Anita, Papp, Diana, Jones, Emily, Sigmond, Timea, Barna, Janos, Traka, Maria H., Lorincz, Tamas, Szarka, Andras, Banhegyi, Gabor, Vellai, Tibor, Korcsmaros, Tamas, Kapuy, Orsolya
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338645/
https://ncbi.nlm.nih.gov/pubmed/30277819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800565RR
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