Urinary concentrating defect in mice lacking Epac1 or Epac2

cAMP is a universal second messenger regulating a plethora of processes in the kidney. Two downstream effectors of cAMP are PKA and exchange protein directly activated by cAMP (Epac), which, unlike PKA, is often linked to elevation of [Ca(2+)](i). While both Epac isoforms (Epac1 and Epac2) are expre...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Cherezova, Alena, Tomilin, Viktor, Buncha, Vadym, Zaika, Oleg, Ortiz, Pablo A., Mei, Fang, Cheng, Xiaodong, Mamenko, Mykola, Pochynyuk, Oleh
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338637/
https://ncbi.nlm.nih.gov/pubmed/30252533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800435R
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