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Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib

The HER family of receptor tyrosine kinases has been linked to deregulation of growth and proliferation for multiple types of cancer. Members have therefore become thefocus of many drug and immune-based therapy innovations. The targeted anti-cancer agent, lapatinib, is a small molecule inhibitor tha...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Showalter, Loral E., Oechsle, Crystal, Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J., Koski, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338365/
https://ncbi.nlm.nih.gov/pubmed/30657766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210209
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