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The Impact of Perineuronal Net Digestion Using Chondroitinase ABC on the Intrinsic Physiology of Cortical Neurons

Perineuronal nets (PNNs) are a form of aggregate Extracellular Matrix (ECM) in the brain. Recent evidence suggests that the postnatal deposition of PNNs may play an active role in regulating neuroplasticity and, potentially, neurological disorders. Observations of high levels of PNN expression aroun...

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Détails bibliographiques
Publié dans:Neuroscience
Auteurs principaux: Chu, Philip, Abraham, Reena, Budhu, Kumarie, Khan, Usma, De Marco Garcia, Natalia, Brumberg, Joshua C.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338339/
https://ncbi.nlm.nih.gov/pubmed/30004010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.07.004
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