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Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology
Alzheimer's disease is the most prevalent tauopathy and cause of dementia. We investigate the hypothesis that reactivation of plasticity can restore function in the presence of neuronal damage resulting from tauopathy. We investigated two models with tau hyperphosphorylation, aggregation and ne...
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| Publicado no: | Exp Neurol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353684/ https://ncbi.nlm.nih.gov/pubmed/25483398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.11.013 |
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