Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth

The endogenous cholinergic system plays a key role in neuronal cells, by suppressing neurite outgrowth and myelination and, in some cancer cells, favoring tumor growth. Platinum compounds are widely used as part of first line conventional cancer chemotherapy; their efficacy is however limited by per...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Cerles, Olivier, Gonçalves, Tânia Cristina, Chouzenoux, Sandrine, Benoit, Evelyne, Schmitt, Alain, Bennett Saidu, Nathaniel Edward, Kavian, Niloufar, Chéreau, Christiane, Gobeaux, Camille, Weill, Bernard, Coriat, Romain, Nicco, Carole, Batteux, Frédéric
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337872/
https://ncbi.nlm.nih.gov/pubmed/30657060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0657-y
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