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Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth
The endogenous cholinergic system plays a key role in neuronal cells, by suppressing neurite outgrowth and myelination and, in some cancer cells, favoring tumor growth. Platinum compounds are widely used as part of first line conventional cancer chemotherapy; their efficacy is however limited by per...
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| Publicado en: | Acta Neuropathol Commun |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6337872/ https://ncbi.nlm.nih.gov/pubmed/30657060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0657-y |
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