Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells

BACKGROUND: The diagnosis of glioblastoma (GBM), a most aggressive primary brain tumor with a median survival of 14.6 months, carries a dismal prognosis. GBMs are characterized by numerous genetic and epigenetic alterations, affecting patient survival and treatment response. Epigenetic mechanisms ar...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Was, Halina, Krol, Sylwia K., Rotili, Dante, Mai, Antonello, Wojtas, Bartosz, Kaminska, Bozena, Maleszewska, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337817/
https://ncbi.nlm.nih.gov/pubmed/30654849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0598-5
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