Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model

BACKGROUND: We set out to determine if the administration of subcutaneous (SQ) ALT-803 was non-inferior to standard intravesical BCG treatment in a carcinogen induced mouse (C57BL/6J) bladder cancer model. METHODS: Using this well-established carcinogen induced mouse model, we studied the effects of...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Furuya, Hideki, Chan, Owen T. M., Pagano, Ian, Zhu, Chengjun, Kim, Nari, Peres, Rafael, Hokutan, Kanani, Alter, Sarah, Rhode, Peter, Rosser, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337786/
https://ncbi.nlm.nih.gov/pubmed/30654801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1778-6
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