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Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization
The retinal disease gene peripherin 2 (PRPH2) is essential for the formation of photoreceptor outer segments (OSs), where it functions in oligomers with and without its homologue ROM1. However, the precise role of these proteins in OS morphogenesis is not understood. By utilizing a knock-in mouse ex...
Gespeichert in:
| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6337695/ https://ncbi.nlm.nih.gov/pubmed/30307502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy359 |
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