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A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies

In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Borcea, Anca-Maria, Marc, Gabriel, Ionuț, Ioana, Vodnar, Dan C., Vlase, Laurian, Gligor, Felicia, Pricopie, Andreea, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337626/
https://ncbi.nlm.nih.gov/pubmed/30621322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010184
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