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A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies

In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Borcea, Anca-Maria, Marc, Gabriel, Ionuț, Ioana, Vodnar, Dan C., Vlase, Laurian, Gligor, Felicia, Pricopie, Andreea, Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337626/
https://ncbi.nlm.nih.gov/pubmed/30621322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010184
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