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The Synergistic Effects of APOE Genotype and Obesity on Alzheimer’s Disease Risk

The APOE gene has three common alleles—E2, E3, and E4, with APOE4 being the strongest genetic risk factor for developing Alzheimer’s Disease (AD). Obesity is a global epidemic and contributes to multiple metabolic problems. Obesity is also a risk factor for cognitive decline. Here, we review the eff...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jones, Nahdia S., Rebeck, G. William
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337558/
https://ncbi.nlm.nih.gov/pubmed/30586872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010063
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