Disclosure of APOE Genotype for Risk of Alzheimer's Disease

BACKGROUND: The apolipoprotein E (APOE) genotype provides information on the risk of Alzheimer's disease, but the genotyping of patients and their family members has been discouraged. We examined the effect of genotype disclosure in a prospective, randomized, controlled trial. METHODS: We rando...

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Autori principali: Green, Robert C., Roberts, J. Scott, Cupples, L. Adrienne, Relkin, Norman R., Whitehouse, Peter J., Brown, Tamsen, Eckert, Susan LaRusse, Butson, Melissa, Sadovnick, A. Dessa, Quaid, Kimberly A., Chen, Clara, Cook-Deegan, Robert, Farrer, Lindsay A., Annas, G., Bhatt, D., Biesecker, B., Blacker, D., Cox, E., Christensen, K., Davis, J.G., Fasaye, G.-A., Griffith, P., Hiraki, S., Juengst, E., Karlawish, J., Linnenbringer, E., Marteau, T., Neimeister, E., Obisesan, T., Petersen, R., Post, S., Ravdin, L., Reilly, R.P., Roter, D., Royal, C., Stern, R., Topol, E., Uhlmann, W., Williams, M., Wright, L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778270/
https://ncbi.nlm.nih.gov/pubmed/19605829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0809578
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