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Myelination in Multiple Sclerosis Lesions Is Associated with Regulation of Bone Morphogenetic Protein 4 and Its Antagonist Noggin

Remyelination is a central aspect of new multiple sclerosis (MS) therapies, in which one aims to alleviate disease symptoms by improving axonal protection. However, a central problem is mediators expressed in MS lesions that prevent effective remyelination. Bone morphogenetic protein4 (BMP4) inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Harnisch, Kim, Teuber-Hanselmann, Sarah, Macha, Nicole, Mairinger, Fabian, Fritsche, Lena, Soub, Daniel, Meinl, Edgar, Junker, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337410/
https://ncbi.nlm.nih.gov/pubmed/30609838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010154
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