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MGMT-Methylation in Non-Neoplastic Diseases of the Central Nervous System

Quantifying O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation plays an essential role in assessing the potential efficacy of alkylating agents in the chemotherapy of malignant gliomas. MGMT promoter methylation is considered to be a characteristic of subgroups of certain malignanc...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Teuber-Hanselmann, Sarah, Worm, Karl, Macha, Nicole, Junker, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068191/
https://ncbi.nlm.nih.gov/pubmed/33917711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083845
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