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A Flexible Synthesis of (68)Ga-Labeled Carbonic Anhydrase IX (CAIX)-Targeted Molecules via CBT/1,2-Aminothiol Click Reaction

We herein describe a flexible synthesis of a small library of (68)Ga-labeled CAIX-targeted molecules via an orthogonal 2-cyanobenzothiazole (CBT)/1,2-aminothiol click reaction. Three novel CBT-functionalized chelators (1–3) were successfully synthesized and labeled with the positron emitter gallium-...

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Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Chen, Kuo-Ting, Nguyen, Kevin, Ieritano, Christian, Gao, Feng, Seimbille, Yann
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337199/
https://ncbi.nlm.nih.gov/pubmed/30577607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010023
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