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Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing mice

Cancer-cachexia (CC) is a wasting condition directly responsible for 20–40% of cancer-related deaths. The mechanisms controlling development of CC-induced muscle wasting are not fully elucidated. Most investigations focus on the postcachectic state and do not examine progression of the condition. We...

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Vydáno v:Physiol Genomics
Hlavní autoři: Blackwell, Thomas A., Cervenka, Igor, Khatri, Bhuwan, Brown, Jacob L., Rosa-Caldwell, Megan E., Lee, David E., Perry, Richard A., Brown, Lemuel A., Haynie, Wesley S., Wiggs, Michael P., Bottje, Walter G., Washington, Tyrone A., Kong, Byungwhi C., Ruas, Jorge L., Greene, Nicholas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337023/
https://ncbi.nlm.nih.gov/pubmed/30289747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00061.2018
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