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Increases in bioactive lipids accompany early metabolic changes associated with β-cell expansion in response to short-term high-fat diet

Pancreatic β-cell expansion is a highly regulated metabolic adaptation to increased somatic demands, including obesity and pregnancy; adult β cells otherwise rarely proliferate. We previously showed that high-fat diet (HFD) feeding induces mouse β-cell proliferation in less than 1 wk in the absence...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Seferovic, Maxim D., Beamish, Christine A., Mosser, Rockann E., Townsend, Shannon E., Pappan, Kirk, Poitout, Vincent, Aagaard, Kjersti M., Gannon, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336958/
https://ncbi.nlm.nih.gov/pubmed/30106624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00001.2018
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