High-fat diet-induced β-cell proliferation occurs prior to insulin resistance in C57Bl/6J male mice

Both short- (1 wk) and long-term (2–12 mo) high-fat diet (HFD) studies reveal enhanced β-cell mass due to increased β-cell proliferation. β-Cell proliferation following HFD has been postulated to occur in response to insulin resistance; however, whether HFD can induce β-cell proliferation independen...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Mosser, Rockann E., Maulis, Matthew F., Moullé, Valentine S., Dunn, Jennifer C., Carboneau, Bethany A., Arasi, Kavin, Pappan, Kirk, Poitout, Vincent, Gannon, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385873/
https://ncbi.nlm.nih.gov/pubmed/25628421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00460.2014
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