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The circadian E3 ligase complex SCF(FBXL3+CRY) targets TLK2
We recently demonstrated that the circadian clock component CRY2 is an essential cofactor in the SCF(FBXL3)-mediated ubiquitination of c-MYC. Because our demonstration that CRY2 recruits phosphorylated substrates to SCF(FBXL3) was unexpected, we investigated the scope of this role by searching for a...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336870/ https://ncbi.nlm.nih.gov/pubmed/30655559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36618-3 |
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